Publications

Ware SA, Kliment CR, Giordano L, Redding KM, Rumsey WL, Bates S, Zhang Y, Sciurba FC, Nouraie SM, Kaufman BA. Cell-free DNA levels associate with COPD exacerbations and mortality. Respir Res. 2024 Jan 18;25(1):42. doi: 10.1186/s12931-023-02658-1. PubMed PMID: 38238743; PubMed Central PMCID: PMC10797855.

Sullivan DI, Bello FM, Silva AG, Redding KM, Giordano L, Hinchie AM, Loughridge KE, Mora AL, Königshoff M, Kaufman BA, Jurczak MJ, Alder JK. Intact mitochondrial function in the setting of telomere-induced senescence. Aging Cell. 2023 Oct;22(10):e13941. doi: 10.1111/acel.13941. Epub 2023 Sep 8. PubMed PMID: 37688329; PubMed Central PMCID: PMC10577573.

Bobba-Alves N, Sturm G, Lin J, Ware SA, Karan KR, Monzel AS, Bris C, Procaccio V, Lenaers G, Higgins-Chen A, Levine M, Horvath S, Santhanam BS, Kaufman BA, Hirano M, Epel E, Picard M. Cellular allostatic load is linked to increased energy expenditure and accelerated biological aging. Psychoneuroendocrinology. 2023 Sep;155:106322. doi: 10.1016/j.psyneuen.2023.106322. Epub 2023 Jun 14. PubMed PMID: 37423094; PubMed Central PMCID: PMC10528419.

Michelson J, Rausser S, Peng A, Yu T, Sturm G, Trumpff C, Kaufman BA, Rai AJ, Picard M. MitoQuicLy: A high-throughput method for quantifying cell-free DNA from human plasma, serum, and saliva. Mitochondrion. 2023 Jul;71:26-39. doi: 10.1016/j.mito.2023.05.001. Epub 2023 May 10. PubMed PMID: 37172669; PubMed Central PMCID: PMC10524316.

Rutledge C, Enriquez A, Redding K, Lopez M, Mullett S, Gelhaus SL, Jurczak M, Goetzman E, Kaufman BA. Liraglutide Protects Against Diastolic Dysfunction and Improves Ventricular Protein Translation. Cardiovasc Drugs Ther. 2023 Jun 29;. doi: 10.1007/s10557-023-07482-9. [Epub ahead of print] PubMed PMID: 37382868; PubMed Central PMCID: PMC10788853.

Zhang M, Feng N, Peng Z, Thapa D, Stoner MW, Manning JR, McTiernan CF, Yang X, Jurczak MJ, Guimaraes D, Rao K, Shiva S, Kaufman BA, Sack MN, Scott I. Reduced acetylation of TFAM promotes bioenergetic dysfunction in the failing heart. iScience. 2023 Jun 16;26(6):106942. doi: 10.1016/j.isci.2023.106942. eCollection 2023 Jun 16. PubMed PMID: 37305705; PubMed Central PMCID: PMC10250906

Rutter GA, Sidarala V, Kaufman BA, Soleimanpour SA. Mitochondrial metabolism and dynamics in pancreatic beta cell glucose sensing. Biochem J. 2023 Jun 15;480(11):773-789. doi: 10.1042/BCJ20230167. Review. PubMed PMID: 37284792.

Rutledge CA, Lagranha C, Chiba T, Redding K, Stolz DB, Goetzman E, Sims-Lucas S, Kaufman BA. Metformin preconditioning protects against myocardial stunning and preserves protein translation in a mouse model of cardiac arrest. J Mol Cell Cardiol Plus. 2023 Jun;4. doi: 10.1016/j.jmccpl.2023.100034. Epub 2023 Apr 5. PubMed PMID: 37425219; PubMed Central PMCID: PMC10327679.

Sturm G, Karan KR, Monzel AS, Santhanam B, Taivassalo T, Bris C, Ware SA, Cross M, Towheed A, Higgins-Chen A, McManus MJ, Cardenas A, Lin J, Epel ES, Rahman S, Vissing J, Grassi B, Levine M, Horvath S, Haller RG, Lenaers G, Wallace DC, St-Onge MP, Tavazoie S, Procaccio V, Kaufman BA, Seifert EL, Hirano M, Picard M. OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases. Commun Biol. 2023 Jan 12;6(1):22. doi: 10.1038/s42003-022-04303-x. PubMed PMID: 36635485; PubMed Central PMCID: PMC9837150.

Sturm G, Monzel AS, Karan KR, Michelson J, Ware SA, Cardenas A, Lin J, Bris C, Santhanam B, Murphy MP, Levine ME, Horvath S, Belsky DW, Wang S, Procaccio V, Kaufman BA, Hirano M, Picard M. A multi-omics longitudinal aging dataset in primary human fibroblasts with mitochondrial perturbations. Sci Data. 2022 Dec 3;9(1):751. doi: 10.1038/s41597-022-01852-y. PubMed PMID: 36463290; PubMed Central PMCID: PMC9719499.

Verma M, Francis L, Lizama BN, Callio J, Fricklas G, Wang KZQ, Kaufman BA, D’Aiuto L, Stolz DB, Watkins SC, Nimgaonkar VL, Soto-Gutierrez A, Goldstein A, Chu CT. iPSC-Derived Neurons from Patients with POLG Mutations Exhibit Decreased Mitochondrial Content and Dendrite Simplification. Am J Pathol. 2022 Nov 19;. doi: 10.1016/j.ajpath.2022.11.002. [Epub ahead of print] PubMed PMID: 36414085.

Carew NT, Schmidt HM, Yuan S, Galley JC, Hall R, Altmann HM, Hahn SA, Miller MP, Wood KC, Gabris B, Stapleton MC, Hartwick S, Fazzari M, Wu YL, Trebak M, Kaufman BA, McTiernan CF, Schopfer FJ, Navas P, Thibodeau PH, McNamara DM, Salama G, Straub AC. Loss of cardiomyocyte CYB5R3 impairs redox equilibrium and causes sudden cardiac death. J Clin Invest. 2022 Sep 15;132(18). doi: 10.1172/JCI147120. PubMed PMID: 36106636; PubMed Central PMCID: PMC9479700.

Tian G, Katchur SR, Jiang Y, Briand J, Schaber M, Kreatsoulas C, Schwartz B, Thrall S, Davis AM, Duvall S, Kaufman BA, Rumsey WL. Small molecule-mediated allosteric activation of the base excision repair enzyme 8-oxoguanine DNA glycosylase and its impact on mitochondrial function. Sci Rep. 2022 Aug 29;12(1):14685. doi: 10.1038/s41598-022-18878-2. PubMed PMID: 36038587; PubMed Central PMCID: PMC9424235.

Rutledge CA, Kaufman BA, Dezfulian C, Elmer J. Metformin protects against cardiac and renal damage in diabetic cardiac arrest patients. Resuscitation. 2022 May;174:42-46. doi: 10.1016/j.resuscitation.2022.03.017. Epub 2022 Mar 21. PubMed PMID: 35331801; PubMed Central PMCID: PMC9050929.

Sidarala V, Zhu J, Levi-D’Ancona E, Pearson GL, Reck EC, Walker EM, Kaufman BA, Soleimanpour SA. Mitofusin 1 and 2 regulation of mitochondrial DNA content is a critical determinant of glucose homeostasis. Nat Commun. 2022 Apr 29;13(1):2340. doi: 10.1038/s41467-022-29945-7. PubMed PMID: 35487893; PubMed Central PMCID: PMC9055072.

Nath S, Caron NS, May L, Gluscencova OB, Kolesar J, Brady L, Kaufman BA, Boulianne GL, Rodriguez AR, Tarnopolsky MA, Truant R. Functional characterization of variants of unknown significance in a spinocerebellar ataxia patient using an unsupervised machine learning pipeline. Hum Genome Var. 2022 Apr 14;9(1):10. doi: 10.1038/s41439-022-00188-8. PubMed PMID: 35422034; PubMed Central PMCID: PMC9010413.